Looks like you have a multi monitor setup, I havent been able to get it to run on the secondary monitor alone in extended mode (as mentioned above).
Are you able to run it on the primary or in clone mode?
and yes, in the case my comp has dual gfx it's been running the game off the intel integrated I can try to force it into discreet, but i'm on playthru 2 right now to see if i can get to ep 3 or 4 without a crash (taking the inori route because it has fewer choices to make so i dont need to baby it)
the game does rely a lot on codecs, we had a ton of problems with demosaicing scenes and getting the dual uniforms to show correctly (looks like i missed a few parts in Ep 1, i'll go thru them again after most people can play without crashing- shouldn't be a hard fix)